Product Details
Description
Greenway supplies tranexamic acid, which is mainly responsible for inhibiting melanin and reducing melanin, thereby preventing pigmentation and preventing dark spots from expanding. It also has the effect of inhibiting inflammation, and is effective for dullness and anti-darkness. It is a fairly multi-channel whitening ingredient. It is used as skin conditioner, moisturizer and whitening agent in cosmetics. The addition amount of this ingredient is usually between 2% and 3%. Many professional bloggers say that it also has certain benefits for rosacea. Generally speaking, it is an ingredient that is more friendly to problem skin.
Solubility
In Vitro |
DMSO:≥50 mg/mL(183.65 mM)
H2O:33.33 mg/mL(122.42 mM;Need ultrasonic) |
Preparing
Stock Solutions
|
Concentration/Solvent/Mass
|
1 mg |
5 mg |
10 mg |
1 mM |
6.3609ml |
31.8046ml |
63.6092ml |
5 mM |
1.2722ml |
6.3069ml |
12.7218ml |
10 mM |
0.6361ml |
3.1805ml |
6.3069ml |
Please refer to the solubility information to select the appropriate solvent. |
Tranexamic acid (Transamin) is an antifibrinolytic for blocking lysine-binding sites of plasmin and elastase-derived
plasminogen fragments with IC50 of 5 mM. Target: OthersTranexamic acid is a synthetic derivative of the amino acid lysine.
Tranexamic acid is frequently used in surgeries with high risk of blood loss such as cardiac, liver, vascular and large
orthopedic procedures. Its oral form is now being evaluated for use in outpatient conditions involving heavy
bleeding.Toxicity/Adverse event: Rare in general, including gastrointestinal effects, dizziness, fatigue, headache, and
hypersensitivity reactions. Use of tranexamic acid has a potential risk of thrombosis. |
Items |
Specifications |
Results |
Appearance |
White crystalline powder |
White crystalline powder |
Solubility
|
Soluble in water and glacial acetic acid, almost not soluble in ethanol and acetone (96%) |
Soluble in water and glacial acetic
acid, almost not soluble in ethanol and acetone (96%) |
Identification
|
Infrared absorption map complies with the tranexamic acid comparison map |
Infrared absorption map complies with the tranexamic acid comparison
map |
PH |
7.0~8.0 |
7.24 |
Loss on drying |
≤0.5% |
0.09% |
Residue on ignition |
≤0.1% |
0.01% |
Heavy metals |
≤10ppm |
<10ppm |
Sulphate ash |
≤0.1% |
<0.03% |
Chloride |
≤140ppm |
<140ppm |
Assay |
99.0%~101.0% |
99.95% |
A≤0.1% |
A=0.043% |
Related substances |
B≤0.2%
C≤0.1% |
B=0.0608%
C=0.009% |
D≤0.1% |
D=0.0051% |
Total impurities(except A,B) ≤0.2% |
Total impurities(except
A,B)=0.015% |
Conclusion:This product conforms to requirements of BP2012 Standard. |
Characteristics
1. Good stability
Compared with traditional whitening ingredients, tranexamic acid has high stability, acid and alkali resistance, and is not easily affected by temperature and environment; it does not need carrier protection, is not affected by the transmission system, and is non-irritating.
2. The skin system is easily absorbed
It is especially suitable for the effects of lightening spots, whitening and balancing the overall skin tone. In addition to lightening spots, tranexamic acid can also improve the overall skin tone transparency and the dullness of local skin patches.
3. It can dilute dark spots, yellow freckles, acne marks, etc.
Dark spots are caused by factors such as UV damage and skin aging, and the body will continue to be manufactured. Tranexamic acid reduces the production of melanin from the basal layer of the epidermis by inhibiting the activity of tyrosinase and melanocytes, and also has a redness effect on inflammation and acne marks.
4. High security
External use is non-irritating to the skin, and the highest concentration in cosmetics is 2% to 3%.
Action and effect
Tranexamic acid is often used as an important whitening ingredient in skin care quality:
Inhibit the darkening, effectively alleviate the black, red, and yellow complexion of the skin, and reduce the melanin deposition.
Effectively diminish acne marks, red blood streaks and purple spots.
Dark skin, darkening and dark circles under the eyes and yellow complexion that is unique to Asians.
Effective treatment and prevention of chloasma.
Moisturizing and hydrating, whitening skin.
http://www.greenwaybiotek.com/